Soheila Kashanian
Professor
Department of Applied Chemistry
Faculty of Chemistry
            Razi University
 
Address: Faculty of Chemistry,
Sensor and Biosensor Research Center (SBRC),& Nanoscience and Nanotechnology Research Center (NNRC),
                 Baghe-Abrisham, Razi University, Kermanshah, Iran.
 
Tel:+98(831)427 4562
Fax:+98(831)4274559
 
 Emails:
kashanian_s? yahoo.com (preferred)
s.kashanian?razi.ac.ir 
 
                  Homepage:http://www.razi.ac.ir/kashanian

 


I. Personal Information:

  • Name: Soheila Kashanian

  • Date of Birth: Sept. 19, 1962

  • Place of Birth: Kermanshah, Iran , preferred

  • Nationality: Iranian



II. Educational Records:

  • B.S. in Chemistry: Shiraz University, Shiraz, Iran, 1982

  • M.S. in Clinical Biochemistry, Tehran University, Tehran, Iran, 1991
  • Ph.D. in Clinical Biochemistry, Tarbiat Modarres University, Tehran, Iran, 2003



 III. Academic Experiences:

    Lab. Instructor

    From April 1983 to June 1988

    Teaching Assistant

    From Sept. 1991 to Aug. 1997

    Head of Chemistry Dept.

    From Sept. 1995 to July 1997

    Ph. D. Candidate at Tarbiat Modaress University, Tehran, Iran

    From Sept. 1997 to Feb. 2003

    Assistant Professor

    From Feb. 2003 to May 2008

    Head of Chemistry Dept.

    From Nov. 2004 to Sept. 2007

    Associate Professor

    From May 2008 to Oct. 2008

    Visitor Research Fellowship
    at Flinders University,
    Adelaide, Australia.

    From Oct. 2008 to Mar. 2009

    Associate Professor

    From Mar. 2009 to Feb. 2013

     Professor
    From Feb. 2013 Continued
     

 IV. Courses Taught:

    Biochemistry (B.Sc., M.Sc. and Ph.D. Chemistry Students)
    Biochemistry (Medicine Students)
    Organic Chemistry (B.Sc. Chemistry Students)
    Clinical Biochemistry (Medical Sciences Students)
    Industrial Biochemistry (Ph.D. Chemical Engineering & Applied Chemistry Students)
    Molecular Biology of the membrane (M.Sc. Biochemistry Students)
    Lipid Metabolism (M.Sc. Biochemistry Students)
    Nanobiotechnology (M.Sc. Applied Chemistry Students)
    Advanced Nanobiotechnology (Ph.D. Applied Chemistry Students)
    Bioorganic Chemistry (Ph.D. Organic Chemistry Students)
    Immunochemistry (Ph.D. Biochemistry Students)
    Biotechnology (Ph.D. Biochemistry Students)

V. Memberships:

1) Academy of Sciences, I.R. Iran 
2) Iranian Chemical Society
3) Iranian Biochemical Society
4) International Federation of Clinical Chemistry (IFCC)

 VI. Laboratory Skills:

  1. HPLC, Spectrofluorimetry, Spectropolarimetry, and other instrumental analysis techniques ( UV, IR, NMR )
  2. Protein Extraction and Purification techniques
  3. Gel Electrophoresis, Blotting
  4. Cell Culture techniques including Cell-Fusion
  5. Immunoassay techniques ( ELISA, EIA, RIA )
  6. DNA extraction and interaction techniques
  7. Nanoparticle Synthesis



VII. Research interests:

  1. Ligand-DNA/Protein interaction
  2. Biosensor/Nanobiosensor design
  3. Drug delivery



VIII. Awards:

1. Distinguished Researcher of Chemistry Faculty, Razi University, 2009 and 2010
2. Distinguished Researcher of Razi University, 2011
3. Distinguished Researcher of Chemistry Faculty, Razi University, 2012

 

 IX. Students Graduated:

M.Sc. Degree


1) Ali Taravati, Purification of Mouse Monoclonal Antidigoxin Antibody and Investigation of Its Stability by Circular Dichroism, Razi University, Sept. 2006.

2) Hadi Ravan, Production of Polyclonal Antibody Against Digoxin and Its Characterization by ELISA & Circular Dichroism, Razi University, Sept. 2007.

3) Hamideh Roshanfekr (Shared), Synthesis, Characterization and DNA Binding Studies of a Palladinum Complex Using Different Instrumental Methods, Sept. 2007.

4) Kani Shalmashi (Shared), Synthesis, Characterization and DNA Binding Studies of a Platinum Complex Using Different Instrumental Methods, Razi University, Nov. 2007.

5) Mehdi Pourfoulad (Shared), Synthesis, Characterization and DNA binding studies of a Platinum(II) complex containing Methyl-substituted 1,10-phenanthroline, Razi University, Feb. 2008.

6) Soyebeh Askari, DNA binding studies of Clodinafob-propargyl and Ethylenethiourea pesticides, Razi University, Sept. 2008.

7) Solmaz Kia, Development of a Rapid Immunochromatography for Detection of Serum Digoxine Using Nanogold, Razi University, Sept. 2008.

8) Jafar Ezzati Nazhad Dolatabadi, Study of DNA Interaction with 2-Tert-Butylhyroquinone and 3-Butylated Hydroxyanisol Foof Additives, Razi University, April 2009.

9) Fereshteh Abasi Tarighat, Biomimetic synthesis of cobalt nanoparticles using apoferritin and its applications, Razi University, Oct. 2009.

10) Ronak Rafipour, The Bio-Nano-Process: Synthesis of cobalt nanoparticles using protein supramolecule for biosensing applications, Razi University, Oct. 2009.

11) Farivash Darabi (shared), Comparative DNA Binding and Gel Electrophoresis Studies of a water soluble Dinitrogen Schiff Base Ligand and Its Cobalt(II) Complex, Razi University, Oct. 2009.

12) Zeinab Ahmadipour (shared), DNA Binding and Gel Electrophoresis Studies of Bis(2,9-Dimethyl-1,10-Phenanthroline)silver(I) Nitrate, Razi University, Oct. 2009.

13) Marzieh Khosravi (shared), DNA interaction studies of a water soluble Nickel (II) complex containing different dinitrogen aromatic ligands using different instrumental methods, Razi University, Feb. 2009.

14) Maryam Mahdavi (shared), Synthesis and DNA interaction studies of new cobalt(II) complexes containing different dinitrogen aromatic ligands with calf thymus DNA using different spectroscopic methods, Razi University, July 2010.

15) Ms. Fariba Jafari (shared), Purification of bovine lactoperoxidase and its immobilization onto polyaniline polymer, Razi University, Sept. 2010.

16) Ms. Sahar Heidary Zeidali, Study of DNA interaction with Tartrazine and Sunset yellow food additives, Razi University, Mar. 2011

17) Ms. Ameneh Tahmasian Ghobadi, Study of DNA interaction with Ethylenediaminetetraaceticacid (EDTA) and Sesamol food additives, Razi University, Apr. 2011.

18) Mr. Abbas Hemati, Preparation and characterization of Solid Lipid Nanoparticle as a drug carrier, Razi University, May 2011.

19) Ms. Zohreh Shariati, Interaction study of 3, 5, 6-Trichloro-2-pyridinol(TCP) with DNA and HSA, Razi University, Sept. 2011

20) Mr. Abd-Al-Ali Ghorbani, Biosensor design based on ferritin direct electron transfer to detect various analytes, Razi University, Oct. 2011.

21) Ms. Sanaz Javanmardi, Study of DNA interaction with Fluoxetine antidepressant, Razi University, Feb. 2012.

22) Ms. Shirin Khorsandi, Study of DNA and HSA interactions with Allura red AC food colorant, Razi University, Jan. 2013.

23) Ms. Sara Pirouznia, Study of DNA and HSA interactions with Desipramine antidepressant, Razi University, Jan. 2013.

24) Ms. Maryam Nazari, Laccase immobilization on the electrode surface to design a biosensor for the detection of phenolic compounds such as catechol, Razi University, Sept. 2013.

Ph.D. Degree


1) Ms. Parvaneh Pakravan (Shared), Spectroscopic studies on the interaction of isatin and synthesized hydrazone derivatives of isatin with deoxyribonucleic acid, Razi University, Mar. 2012.

2) Ms. Hamideh Roshanfekr (Shared), Study of DNA cleavage, cytotoxicity and ligand dependent interactions of five mixed ligand copper(II) complexes with DNA in solution and on DNA-based electrochemical biosensor using chitosan carbon nanotubes composite as an immobilization platform, Razi University, Jan. 2013.

3) Ms. Fahimeh Kheirdoosh (Shared), Interaction study of aspartame, an artificial sweetener, and its copper(II) complex with DNA and HSA, Razi University, Oct. 2013.


 X. Current Ph.D. Students:

1) Ms. Elham Rostami
2) Ms. Ronak Rafipour
3) Mr. Abbas Hemati
4) Ms. Nasim Malekii
5) Mr. Gholamreza Ghalekhani
6) Ms. Maryam Nazari


 XI. Books:

1. K.Omidfar, M. Pahnejad and S. Kashanian, An overview on immunochemistry methods and their applications in clinical diagnosis (in Persian), Vista publications, Tehran University of Medical Sciences, Tehran, Iran, 2010.

2. K.Omidfar, M. Pahnejad and S. Kashanian, M. R. Ostadali, An overview of basic techniques and specialized applications of cell culture (in Persian), Vista publications, Tehran University of Medical Sciences, Tehran, Iran, 2011.


 XII. Patent :

K. Omidfar, M.J. Rasaee, S. Kashanian and M. Paknejad, Manner of conjugate stabilization of Penicillinase Enzyme and coated antibody on plate, in the solution state and at 4?C for application in immunoassay measurement, Invention Registration Book No. 27989, June 17, 2002.


 XIII. Workshops Attended/ Directed :

1. Directed the workshop entitled "Production And Large Scale Preparation of Monoclonal Antibodies to be Used as Diagnostic And Treatment Reagent", Organized by Department of Medical Biotechnology, School of Medical Sciences, Tarbiat Modarres University, Tehran, I.R.IRAN (2003).

2. Attended the workshop entitled "Real-Time PCR", Organized by BioFlox Japan and Far Gene Pouyesh Ltd., Department of Biochemistry, School of Medical Sciences, Tarbiat Modarres University, Tehran, I.R.IRAN, Sept. 13,14 (2005).

3. Attended the workshop entitled "Production of Recombinant Protein (Gene to Protein)", Organized by Center for Research and Development of Biotechnology (CRDB) in Collaboration with Institute for research and planning of Higher Education and Department of Biotechnology, School of Medical Sciences, Tarbiat Modarres University, Tehran, I.R.IRAN, March 11-14 (2006).

4. Directed the workshop entitled “Applied of Immunochemistry Techniques in Clinical Diagnostic Using ELISA and RIA", Organized by Endocrinology and Metabolism Research Center (EMRC), Tehran University of Medical Sciences, Tehran I.R. IRAN, Nov. 14-16 (2006).

5. Directed the workshop entitled "Cellular Technology Using Immunological Methods in Clinical Diagnostic", Endocrinology and Metabolism Research Center (EMRC), Tehran University of Medical Sciences, Tehran I.R. IRAN, July 3-5 (2007).


 XIV. List of Publications: :

1. M.B. Gholivand, S. Kashanian and M. Shamsipur, Spectrophotometric Study of Some Alkaline Earth and of Silver Complexes with Dibenzo-30-crown-10 in Methanol, Dimethylformamide and Dimethylsulfoxide Solutions, Polyhedron, 6 (3), 535-538, 1987.

2. S. Kashanian, A. Nikrahi and M. Shamsipur, Spectrophotometric Studies of Alkaline Earth Complexes with 1,10-Diaza-18-crown-6 and Cryptand C222 in Some Nonaqueous Solutions, Iran. J. Sci. Technol., 12 (2&3), 105-110, 1988.

3. S. Kashanian, M.B. Gholivand, S. Madaeni, A. Nikrahi and M. Shamsipur, Spectrophotometric Study of the Complexation Reactions Between Alkaline Earth Cations and Murexide in Some Nonaqueous Solutions, Polyhedron, 7 (14)1227-1230, 1988.

4. S. Kashanian and M. Shamsipur, Complex Formation of Alkaline Earth Cations with Benzo-15-crown-5 and Some 18-Crowns in Methanol, Dimethlyformamide and Dimethylsulfoxide Solutions, Inorg. Chim. Acta, 155 (2) 203-206, 1989

5. M. Shamsipur, S. Madaeni and S. Kashanian, Spectrophotometric Study of Alkali Metal-Murexide Complexes in Some Nonaqueous Solutions, Talanta, 36 (7) 773, 1989.

6. A. Rabbani, S. Kashanian and S. Rezaei, Thermal Denaturation of High Mobility Group Proteins (HMG2) and the Interaction of its subfractions with Deoxyribonucleic Acid, Iran. J. Sci. Technol. Trans. A, 20 (2), 241-250, 1996.

7. S. Kashanian, M.J. Rasaee and M. Paknejad, Anti-Digoxin monoclonal antibody, Hybridoma and Hybridomics, 21 (3), 219, 2002.

8. S. Kashanian, M.J. Rasaee, M. Paknejad, K. Omidfar, M. Pour-Amir and M. Rajabi Bazl, Preparation and Characterization of Monoclonal Antibody against Digoxin, Hybridoma and Hybridomics, 21 (5), 375-379, 2002.

9. M. Paknejad, M.J. Rasaee and S. Kashanian, Anti-MUC1-Monoclonal Antibody, Hybridoma and Hybridomics, 21 (6), 491, 2002.

10. M. Paknejad, M.J. Rasaee, F. Karami Tehrani, S. Kashanian, M.A. Mohagheghi, K.Omidfar and M. Rajabi Bazl, Production of Monoclonal Antibody, PR81, Recognizing the Tandem Repeat Region of MUC1 Mucin, Hybridoma and Hybridomics, 22 (3), 153-158, 2002.

11. Sh. Hallaj, M.J. Rasaee, M.S. Haerian, M. Paknejad, S. Kashanian, F. Rahbarizadeh, K. Omidfar, M. Malekaneh and M. Kakhki, A heterologous enzyme linked immunosorbant assay of morphine using penicillinase as lable, Iranian Journal of Biotechnology, 1 (4 ), 239 -246, 2003.

12. K. Omidfar, M.J. Rasaee, H. Modjtahedi, M. Forouzandeh, M. Taghikhani, A. Bakhtiari, M. Paknejad and S. Kashanian, Production and characterization of a new antibody specific for the mutant EGF receptor, EGFRvIII, in camelus Bactrianus, Tumor Biol., 25, 179-187, 2004.

13. N. Golmakany, M.J. Rasaee, B. Forouzandeh, A. Shojaosadati, S. Kashanian and K. Omodfar, Continuous production of Monoclonal Antibody in a Packed-bed Bioreactor, Biotechnology and Applied Biochemistry, 41 (pt 3), 273-8, 2005.

14. Z. Farahnejad, M.J. Rasaee, M.F. Moghadam, M. Paknejad, S. Kashanian and M. Rajabi, Preparation and characterization of a monoclonal antibody against mannoprotein of Candida Albicans, Hybridoma (Larchmt), 24(3), 146-51, 2005.

15. K. Omidfar, Su. Kashanian, M. Paknejad, S. Kashanian, B. Larijani, H. Roshanfekr, Production and characterization of Monoclonal Antibody against Human Serum Albumin, Hybridoma, 26(4), 215, 2007.

16. H. Rooki, K. Khajeh, A. Mostafaie, S. Kashanian and S. Ghobadi, Partially Folded Conformations of Bovine Liver Glutamate Dehydrogenase Induced by Mild Acidic Conditions, J. Biochem. 142, 193, 2007.

17. K. Omidfar, M.J. Rasaee, S. Kashanian, M. Paknejad and Z. Bathaie, Studies of Thermostability in Camelus Bactrianus (Bactrian Camel) Single-domain Antibody Specific for the Mutant Epidermal-growth-factor Receptor Expressed by Pichia, Biotechnol. Appl. Biochem., 46, 41, 2007.

18. S. Kashanian, M.B. Gholivand, F. Ahmadi, A. Travati and A. Hosseinzadeh, DNA Interaction with A1-N,N’- -phenylendiamine complex, Spectochimica Acta A, 67, 472, 2007.

19. S. Kashanian, H. Ravan, S. Ghobadi, K. Omidfar and S. Askari, Structural and Functional Study of Rabbit Polyclonal Antibody for Immunoassay Purposes, Hybridoma, 27(1), 48, 2008.

20. S. Kashanian, S. Ghobadi, K. Omidfar and H. Ravan, Structural and Functional Study of Mouse Monoclonal Antidigoxin Antibody Against Thermal Variation, Hybridoma, 27(2), 123-130, 2008.

21. S. Kashanian, N. Shahabadi, H. Roshnfekr, K. Shalmashi and K. Omidfar, DNA Binding Studies of PdCl2(LL) (LL = Chelating Diamine Ligand: N,N-Dimethyl Trimethylen Diamine) Complex, Biochemistry (Moscow), 73(8), 929-936, 2008.

22. S. Kashanian, M. Paknejad, S. Ghobadi, K. Omidfar and H. Ravan, Effect of Osmolytes on the Conformational Stability of Mouse Monoclonal Antidigoxin Antibody in Long Term Storage, Hybridoma, 27(2), 99-106, 2008.

23. S. Kashanian, M.B. Gholivand, F. Ahmadi and H. Ravan, Interaction of Diazinon with DNA and the Protective Role of Selenium in DNA Damage, DNA and Cell Biology, 27(6), 325-332, 2008.

24. S. Kashanian, S. Askari, F. Ahmadi, K. Omidfar, S. Ghobadi and F. Abasi Tarighat, In Vitro study of DNA Interaction with Clodinafop-Propargyl Herbicide, DNA and Cell Biology, 27(10), 581–586, 2008.

25. K. Omidfar, Z. Moinfar, A. Naderi Sohi, S. M. Tavangar, V. Haghpanah, R. Heshmat, S. Kashanian, Bagher Larijani, Expression of EGFRvIII in Thyroid Carcinoma: Immunohistochemical Study by Camel Antibodies, Immunological Investigations,38 (2), 165-180, 2009.

26. N. Shahabadi, S. Kashanian and Mehdi Purfoulad, DNA interaction studies of a platinum(II) complex, PtCl2(NN) (NN = 4,7-dimethyl-1,10-phenanthroline), using different instrumental methods, Spectrochimica Acta Part A, 72 (4), 757-76, 2009.

27. S. Kashanian and J. Ezzati Nazhad Dolatabadi, DNA Binding Studies of 2- tert- Butylhydroquinone (TBHQ) Food Additive, Food Chemistry, 116, 743–747,

2009. 28. S. Kashanian and J. Ezzati Nazhad Dolatabadi, In vitro study of CT-DNA interaction with butylated hydroxyanisole (BHA), DNA and Cell Biology, 28(10), 535–540, 2009.

29. N. Shahabadi, S. Kashanian, K. Shalmashi and H. Roshnfekr, DNA interaction with PtCl2(LL) (LL = Chelating Diamine Ligand: N,N-Dimethyl Trimethylen Diamine) Complex, Applied Biochemistry and Biotechnology, 158, 1-10, 2009.

30. N. Shahabadi, S. Kashanian and F. Darabi, In vitro study of DNA interaction with a Water-Soluble Dinitrogen Schiff Base, DNA and Cell Biology, 28(11), 589–596, 2009.

31. N. Shahabadi, F. Darabi, M. Maghsudi, S. Kashanian, DNA Binding and Gel Electrophoresis Studies of a Copper (II) Complex Containing Mixed Aliphatic and Aromatic Dinitrogen Ligands, DNA and Cell Biology, 29(6), 329-336, 2010.

32. K. Omidfar, S. Kia, S. Kashanian, M. Paknejad, A. Besharatie, Su. Kashanian and B. Larijani, Colloidal Nanogold-Based Immunochromatographic Strip Test for the Detection of Digoxin Toxicity, Applied Biochemistry and Biotechnology, 160, 843–855, 2010.

33. S. Kashanian, J. Ezzati Nazhad Dolatabadi, In Vitro studies on calf thymus DNA interaction and 2-tert-butyl-4-methylphenol (TBMP) food additive, European Food research and Technology, 230 (6), 821-825, 2010.

34. J. Ezzati Nazhad Dolatabadi. S. Kashanian, A review on DNA interaction with synthetic phenolic food additives, Food Research International, 43 (5), 1223–1230, 2010.

35. S. Kashanian, M.M. Khodaei, P. Pakravan, Spectroscopic Studies on the Interaction of Isatin with Calf Thymus DNA, DNA and Cell Biology, 29 (10): 639-646, 2010.

36. S. Kashanian, F. Harding, Y. Irani, S. Klebe, K. Marshall, A. Loni, L. Canham, D. Fan, K. A. Williams, N. H. Voelcker, J. L. Coffer, Evaluation of mesoporous silicon polycaprolactone composites as ophthalmic implants, Acta Biomaterialia, 6 (9), 3566-3572, 2010.

37. N. Shahabadi, S. Kashanian and F. Darabi, DNA binding and DNA cleavage studies of a water soluble cobalt (II) complex containing dinitrogen Schiff base ligand: The effect of metal on the mode of binding, European Journal of Medicinal Chemistry,45, 4239-4245, 2010.

38. N. Shahabadi, S. Kashanian, M. Khosravi, M. Mahdavi, Multispectroscopic DNA interaction studies of a water soluble nickel(II) complex containing different dinitrogen aromatic ligands, Transition Metal Chemistry, 35, 699-705, 2010.

39. N. Shahabadi, S. Kashanian, Z. Ahmadipour, DNA Binding and Gel Electrophoresis Studies of a 4 New Silver(I) Complex Containing 2,9-dimethyl- 5 1,10- Phenanthroline Ligands, DNA and Cell Biology, 30 (3), 187-194, 2011.

40. S. Kashanian, M.M. Khodaei, H. Roshanfekr, N. Shahabadi A. Rezvani, Gh. Mansouri, DNA-Binding, DNA cleavage and Cytotoxicity Studies of New Copper (II) Complexes, DNA and Cell Biology, 30 (5), 287-296, 2011.

41. N. Shahabadi, S. Kashanian, M. Mahdavi, DNA Interaction Studies of Cobalt (II) Mixed-Ligand Complexes Containing Dimethyl-1, 10-Phenanthroline and Dipyrido[3,2-a:2?,3?-c] Phenazine: The Role of Methyl Substitutions on the Mode of Binding, DNA and Cell Biology, 30 (7): 507-515, 2011.

42. Gh. Dehghan, J. Ezzati Nazhad Dolatabadi, A. Jouyban, K. Asadpour Zeynali, S. M. Ahmadi, S. Kashanian, Spectroscopic Studies on the Interaction of Quercetin–Terbium(III) Complex with Calf Thymus DNA, DNA and Cell Biology, 30 (3), 195-20, 2011.

43. M.B. Gholivand, S. Kashanian, H. Peyman, H. Roshanfekr, DNA-Binding study of Anthraquinone derivatives using Chemometrics methods, European Journal of Medicinal Chemistry, 46 (7), 2630-2638, 2011.

44. S. M. Ahmadi, Gh. Dehghan, M. A. Hosseinpourfeizi, J. Ezzati Nazhad Dolatabadi, S. Kashanian, Preparation, Characterization, and DNA Binding Studies of Water-Soluble Quercetin–Molybdenum(VI) Complex, DNA and Cell Biology, 30 (7): 517-523, 2011.

45. S. Kashanian, S. Heidary Zeidali, DNA Binding Studies of Tartrazine Food Additive, DNA and Cell Biology, 30 (7), 499-505, 2011.

46. S. Kashanian, A. Tahmasian Ghobadi, DNA interaction studies of Ethylenediaminetetraaceticacid Food Additive and Selenium effect in DNA Cleavage-Inhibition, DNA and Cell Biology, 30(12), 1085-1090, 2011.

47. N. Shahabadi, S. Kashanian, M. Mahdavi and N. Sourinejad, DNA Interaction and DNA Cleavage Studies of a New Platinum (II) Complex Containing Aliphatic and Aromatic Dinitrogen Ligands, Bioinorganic Chemistry and Applications, 2011, Article ID 525794, 1-10, 2011.

48. N. Shahabadi, S. Kashanian and A. Fatahi, Identification of binding mode of a platinum (II) complex, PtCl2(DIP) (DIP = 4,7-diphenyl-1,10-phenanthroline) and calf thymus DNA, Bioinorganic Chemistry and Applications, 2011, Article ID 687571, 1-7, 2011.

49. S. Kashanian, A. Hemati Azandaryani, K. Derakhshandeh, New surface modified solid lipid nanoparticles using N-glutaryl phosphatidylethanolamine as outer shell, International Journal of Nanomedicine, 6, 2393-2401, 2011.

50. S. Kashanian, M.M. Khodaei, H. Roshanfekr, N. Shahabadi, Gh. Mansouri, DNA Binding, DNA Cleavage and Cytotoxicity Studies of a New Water Soluble Copper(II) Complex: The Effect of Ligand Shape on the Mode of Binding, Spectrochimica Acta Part A, 86, 351-359, 2012.

51. M.B. Gholivand, S. Kashanian, H. Peyman, DNA Binding, DNA Cleavage and Cytotoxicity Studies of two Anthraquinone derivatives, Spectrochimica Acta Part A, 87, 232-240, 2012.

52. S. Kashanian, M.M. Khodaei, P. Pakravan, H. Adibi, Molecular aspects on the interaction of isatin-3-isonicotinylhydrazone to deoxyribonucleic acid: Model for intercalative drug- DNA binding, Mol. Biol. Report, 39(4), 3853-3861, 2012.

53. S. Kashanian, R. Rafipour, F. Abasi Tarighat, H. Ravan, Immobilization of cobaltferritin onto gold electrode based on self-assembled monolayers, IET Nanobiotechnology, 2012, 6(3), 102–109, 2012.

54. S. Kashanian, Z. Shariati, H. Roshanfekr, S. Ghobadi, DNA Binding Studies of 3, 5, 6-Trichloro-2-pyridinol (TCP) Pesticide Metabolite, DNA and Cell Biology, 31(7): 1341-1348, 2012.

55. S. Kashanian, S. Javanmardi, A. Chitsazan, K. Omidfar, M. Paknejad, DNA binding studies of Fluoxetine antidepressant, DNA and Cell Biology, 31(7): 1349-1355, 2012.

56. S. Kashanian, S. Javanmardi, A. Chitsazan, M. Paknejad, K. Omidfar, Fluorometric study of Fluoxetine DNA binding, Journal of Photochemistry & Photobiology, B: Biology, 113, 1-6, 2012.

57. S. Kashanian, S. Heidary Zeidali, K. Omidfar, N. Shahabadi, Multi-spectroscopic DNA interaction studies of sunset yellow food additive, Mol. Biol. Report, 39(12):10045-10051, 2012.

58. S. Kashanian, F. Abasi Tarighat, R. Rafipour, M. Abbasi-Tarighat, Biomimetic synthesis and characterization of cobalt nanoparticles using apoferritin, and investigation of direct electron transfer of Co(NPs)-Ferritin at modified glassy carbon electrode to design a novel nanobiosensor, Mol. Biol. Report, 39 (9): 8793-8802, 2012.

59. F. Jafary, S. Kashanian, Z. Samsam Sharieat, F. Jafary, K. Omidfar, M. Paknejad, Stability improvement of immobilized lactoperoxidase using polyaniline polymer, Mol. Biol. Report, 39(12):10407-10412, 2012.

60. S. Kashanian, A. Tahmasian Ghobahi, Z. Shariati, H. Roshanfekr, DNA Interaction Studies of Sesamol (3, 4-methylenedioxyphenol) Food Additive, Mol. Biol. Report, 40(2):1173-1179, 2013.

61. P. Pakravan, S. Kashanian, M. M. Khodaei, F. J. Harding, Biochemical and pharmacological characterization of isatin and its derivatives: From Structure to Activity, Pharmacol. Report, 65(2):313-335, 2013 F. Khorsand, S. Riahi, S. Eynollahi Fard, S. Kashanian, A. Naeemy, B. Larijani, K

62.Omidfar, Development of a 3-hydroxybutyrate dehydrogenase enzyme biosensor based on carbon nanotube modified screen-printed electrode, IET Nanobiotechnology, 7(1): 1-6, 2013.

63. S. Kashanian, M.M. Khodaei, F. Kheirdoosh, Journal of Photochemistry & Photobiology B: Biology, In Vitro DNA binding studies of Aspartame, an artificial sweetener, 120: 104–110, 2013.

64. S. Vandghanooni, A. Barzegari, M. Eskandani, A. Forouharmehr, V. Kafil, S. Kashanian, J. Ezzati Nazhad Dolatabadi, Cytotoxicity and DNA fragmentation properties of butylated hydroxyanisole, DNA and Cell Biology, 32(3):98-103, 2013.

65. S. Kashanian, M. M. Khodaei, H. Roshanfekr, H. Peyman, DNA interaction of [Cu(dmp)(phen-dion)] (dmp = 4,7 and 2,9 dimethyl phenanthroline, phen-dion = 1,10-phenanthroline-5,6-dion) complexes and DNA-based electrochemical biosensor using chitosan-carbon nanotubes composite film, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 114: 642–649, 2013.

66. F. Jafary, S. Kashanian, S. Z. Samsam Sharieat, Purification, immobilization andcharacterization of bovine lactoperoxidase, International Journal of Food Properties, In press, DOI:10.1080/10942912.2011.566400

67. M. Eskandani, S. Khani, S. Kashanian, H. Hamishehkar, and J. Ezzati Nazhad Dolatabadi, Geno- and cytotoxicity of propyl gallate food additive, Drug and Chemical Toxicology, Accepted 2013.

68. R. Rafipour, S. Kashanian, F. Abasi Tarighat Sensitive electrochemical biosensing of H2O2 based on cobalt nanoparticles synthesized in iron storage protein molecules, ferritin, , IET Nanobiotechnology, Accepted 2013.

69. N. Shahabadi, M. M. Khodaei, S. Kashanian, F. Kheirdoosh, Interaction of a Copper(II) Complex containing an artificial sweetener (aspartame) with calf thymus DNA, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, Accepted 2013.

70. H. Ravan, S. Kashanian, N. Sanadgol, A. Badoei-Dalfard Z. Karami, Strategies for optimizing DNA hybridization on surfaces, Analytical Biochemistry, 444: 41–46, 2014.

71. S. Kashanian, M. M. Khodaei, H. Roshanfekr, Gh. Mansouri, Interaction of two new mixed ligand Copper(II) Complexes with DNA Probed by thermodynamic and spectroscopic studies, Mol. Biol. Report, Accepted 2013.

72. E. Rostami, S. Kashanian, M. Askari, The effect of ultrasound wave on levothyroxine release from chitosan nanoparticles, Advanced Materials Research 829 (2014) 284-288


 XV. List of Papers Presented in National and International Conferences: :

1. S. Kashanian, M.B. Gholivand, A. Nikrahi and M. Shamsipur, Spectrophotometric Study of Alkaline Earth Cation-Murexide Complexes in Methanol, Dimethyl-formamide and Dimethylsulfoxide Solutions, Second Iranian Chemistry & Chemical Engineering Congress, Ferdowsi University, Mashhad, Iran, Sept. 6-9, 1987. Paper Abstracts p. 49.

2. S. Kashanian, M.J. Rasaee, M. Paknejad and A. Zavaran, A new tracer for Digoxin detection in immunoassay , 9th APCCB & 28th Annual Conference of ACBI, New Delhi, India, March 9-14, 2002. Paper Abstracts p. 262.

3. S. Kashanian, M.J. Rasaee, A. Zavaran Hoseyni, N. Nazem and M. Paknejad, Specific Anti-Digoxin Antibody, 16th Iranian Congress of Physiology & Pharmacology, Tarbiat Modarres University, Tehran, Iran, May 9-13, 2003. Paper Abstracts, p. 101.

4. M. Paknejad, M.J. Rasaee, F. Karami Tehrani, M.A. Mohagheghi and S. Kashaniasn, Monoclonal Antibody against MUC1, ibid, p. 90.

5. S. Kashanian, M.J. Rasaee, M. Paknejad and A. Zavaran, Specific detection of anti-digoxin monoclonal antibody using Digoxin- C3´-Penicillinase tracer, 15th IFCC-FESCC European Congress of Clinical Chemistry and Laboratory Medicine & 22nd National Congress of the Spanish Society of Clinical Biochemistry and Molecular Pathology, Barcelona, Spain, June 1-5 ,2003. Poster Abstracts, p. S 396.

6. M. Rajabi Bazl, M.J. Rasaee, S. Kashanian, and M. Paknejad, Enzyme-linked immunosorbent assay of Morphine using yolk immunoglobulin,3rd Iranian Congress of Biotechnology, Ferdowsi University, Mashad, Iran, Sept. 9-11, 2003. Paper Abstracts pp. 49- 51.

7. N. Golmakani, M.J. Rasaee, M. Forouzandeh, A. Shojasadati, S. Kashanian and E. Sadroddiny, Kinetic of cell growth and antibody production in rolling bottle, ibid, pp. 360-362.

8. S. Kashanian, M.J. Rasaee, M. Paknejad, K. Omidfar and M. Rajabi, A monoclonal antibody, PR81, directed against the tandem repeat region of MUC1: Production and Immunocytochemical characterization, the 7th Iranian Congress of Biochemistry, Ahwaz, Iran, Jan. 26-29, 2004. Paper Abstracts, p. 200.

9. K. Omidfar, M.J. Rasaee, M. Fourouzandeh, M. Taghikhani, H. Modjtahedi, M. Paknejad and S. Kashanian, Heavy chain antibodyies on a promising factor for recognizing EGFRv III expressing cell and tumor diagnostic, ibid, p. 201.

10. M. Rajabi Bazl, M.J. Rasaee, M. Paknejad and S. Kashanian, Purification of chicken antibody against morphin using PEG fractionation method, ibid, p. 268.

11. M. Paknejad, M.J. Rasaee, S. Kashanian, K. Omidfar, M. Rajabi Bazl, N. Golmakani, Preparation and characterization of monoclonal antibody agaist digoxin using penicillinase as label, ibid, p. 177.

12. Paknejad, M.J. Rasaee, S. Kashanian and K. Omidfar, Preparation of Monoclonal Antibody Against Tandem Repeat Reagion of MUC1, The 7th Congress of Immunology & Allergy, Mashhad, Iran, May 4-7 2004. Paper Abstracts, No. 72.

13. K. Omidfar, M.J. Rasaee, M. Forouzandeh, M. Taghikani, S. Kashanian and A. Taravati, Thermostability study of camelus bactrianus heavy chain and VHH antibodies specific for de 2-7 EGFR, 2005 FEBS Congress and IUBMB Conference, Budapest, Hungry, June 3-8, 2005. Paper Abstracts, p. 39.

14. A. Taravati, S. Kashanian, S. Ghobadi and A. Hosseinzadeh Colagar, Purification of mouse monoclonal antibody using protein G affinity matrix, 13th Iranian Biology Conference and the first International Conference of Biology, Rasht, I.R. Iran, August 23-25, 2005. Paper Abstracts p. 20.

15. L. Atazadeh, S. Kashanian and M. Sharifi, Influence of zinc on productivity and species composition in algal periphyton communities-an experimental evaluation, ibid,p.228.

16. N. Shahabadi and S. Kashanian, Investigation of some oxidative reactions of alkyl halides on platinum(II) complexes and kinetic studies, 11th Asian Chemical Congress, Seoul, Korea, August 24-26, 2005. Paper Abstracts p. 346.

17. S. Kashanian, Studies of thermostability of monoclonal antibody against Digoxin, ECB12 - 12th European Congress on Biotechnology, Copenhagen, Denmark, August 2005. Abstracts in Journal of Biotechnology p. S29.

18. H. Rooki, K. Khajeh, S. Kashanian and S. Ghobadi, Partially folded conformation of bovine liver glutamate dehydrogenase induced by mild acidic conditions, 8th Iranian Congress of Biotechnology and the first International congress of Biochemitry & Molecular Biology, Tehran, I.R.Iran, September 11-15, 2005. Paper Abstracts p. 51.

19. Alirezapour, M.J. Rasaee, S. Kashanian, K. Omidfar and E. Sadroddiny, Production of single chain FV antibody against digoxin, ibid, p. 109.

20. S. Kashanian, A. Taravari, M. Paknejad and Javad Mohammadnejad, Affinity stability of monoclonal antibody against thermal variations, 1st chemical congress, Budapest, Hungary, August 27-31,2006. Paper Abstracts, p. 385

21. K. Omidfar, A. Besharati, S. Kia, S. Kashanian, B. Larijani, M. Paknejad, Development of rapid one-step immunochromatography assay for detecting urinary albumine, 12th Asian Chemical Congress, Kuala Lampur, Malaysia, Aug. 23-25, 2007. Paper Abstracts, p. 424.

22. N. Shahabadi, S. Kashanian and H. Roshanfekr, Interaction of PdCl2(LL) (LL= (Chelating Diamine Ligand)) Complex with DNA, ibid, p. 20.

23. M. Paknejad, K. Omidfar, S. Kashanian, P. Pasalar and Sh. Khaghani, Preparation of Morphine-CBSA Conjucate as an Immunogen, ibid, p. 356.

24. S. Kashanian, H. Ravan, K. Omidfar and N. Paknejad, Production and Structural Study of High Affinity Polyclonal Anibody Against Digoxin, ibid, p. 346.

25. N. Shahabadi, S. Kashanian and K. Shalmashi, Interaction of PtCl2(LL)(LL = (Chlating Diamine Ligand)) Complex with DNA, ibid, p. 16.

26. S. Kia, K. Omidfar, S. Kashanian, A. Besharati and B. Larijani, Development of Rapid One-Step Assay for Detecting digoxin Toxicity, Eurotox, Amesterdam, The Nederland’s, Oct. 7-10, 2007, Toxicology Letters, 172(Supplement1), p. S82-S83

27. F. Ahmadi, S. Kashanian and M. B. Gholivand, Interaction of Diazinon with DNA, ibid, p. S205

28. S. Kashanian, H. Ravan and K. Omidfar, Antidote Property of Polyclonal Antibody against Digoxin Toxicity, ibid, p. S147

29. M. Paknejad, M. Sukhtanloo, K. Omidfar, S. Kashanian, P. Pasalar and Sh. Khaghani, Preparation of Monoclonal Antibody Against Morphine, 11th Asian-Pacific Congress of Clinical Biochemistry, October 14-19, 2007, Beijing, China, Chin. Med. J. 120, Supplement 2, 100.

30. S. Kashanian, N. Shahabadi, H. Roshanfekr, K. Shalmashi H. Ravan, Inverstigation of DNA Interaction with Palladium Chloride-N, N-Dimethyltrimethylene Diamine (Pd Cl2-LL) by Fluorescence and UV Absorption, The 9th Iranian Congress of Biochemistry & the 2nd International Congress of Biochemistry and Molecular Biology, Shiraz University, Iran, October 29, 2007. Paper Abstracts, p. S196.

31. H. Ravan, S. Kashanian, S. Askary and N. Sandgol, Production and Purification of Rabbit Anti-IgY Antibody, ibid, p. S264.

32. M. Paknejad, K. Omidfar, S. Kia, S. Kashanian, A. Besharati, S. Kashanian and B. Larijani, Characterization of Monoclonal Antibody Against Human Serum Albumin, ibid, p. S274.

33. K. Shalmashi, N. Shahabadi, S. Kashanian and H. Roshanfekr, Interaction of PtCl2(LL) (LL = (Chelating Diamine Ligand)) Complex with DNA, 9th Iranian Inorganic Chemistry Conference, Semnan University, Iran, March 7, 2007. Paper Abstracts, p. 179.

34. H. Roshanfekr, S. Kashanian, N. Shahabadi and K. Shalmashi, Interaction of PdCl2(LL) (LL = (Chelating Diamine Ligand)) Complex with DNA, ibid, p. 133.

35. S. Kashanian, J. Ezzati Nazhad Dolatabadi, Investigation of DNA interaction with Tert-Butyl Hydroquinone using Fluorimetry, 2nd Euchem Congress, Turin, Italy, September 16-20, 2008.

36. S. Kashanian, F. Abasi Tarighat, R. Rafipour, S. Askari,H. Ravan, Fabrication of cobalt nanoparticles in the biotemplate, Apoferritin cavity, ibid

37. S. Kashanian, J. Ezzati Nazhad Dolatabadi, Mehdi Zahedi, Marziyeh Sadeghi Voltammetric studies of interaction of 2-tert Butylhydroquinone with DNA, ibid.

38. S. Kashanian, S. Askari, F. Ahmadi, A. Fatahi, H. Roshanfekr DNA Binding Studies of Clodinafop-Propargyl using Fluorimetry, ibid.

39. N. Shahabadi, S. Kashanian, M. Purfoulad, DNA binding studies of a platinum (II) complex, PTCL2(NN) (NN 4,7-dimethyl 1,10-phenanthroline), using different instrumental methods, The 13th International Biotechnology Symposium (IBS) and Exhibition IBS-2008. October 12nd – 17th, 2008. Dalian World Expo Centre, Dalian, China, Journal of Biotechnology, 136(Supplement 1), S92-S93 (2008).

40. N. Shahabadi, S. Kashanian, A. Fatahi, Fluorescence spectroscopy, UV–vis spectrophotometric, and voltametric studies of the competitive interaction of Tris(batho-phenanthrolin)nickel(II) complex and neutral red with DNA, ibid, S62.

41. N. Shahabadi, S. Kashanian, A. Fatahi, Identification of binding mode of a PT (II) complex, PTCL2 (NN) (NN = 4,7-diphenyl 1,10 phenanthroline), and calf thymus DNA, Journal of Biotechnology, ibid, S105.

42. S. Kashanian, F. Abasi Tarighat, R. Rafipour, Apoferitin-Mediated Synthesis of Uniform Cobalt Nanoparticles, 2nd International Congress on Nanoscience and Nanotechnology Faculty of Chemistry, University of Tabriz, 28-30 October 2008.

43. N. Shahabadi, S. Kashanian, F. Darabi Synthesis of a water soluble Schiff base, N, N'-bis {5-[(triphenylphosphonium)-methyl] salicylidine}-ophenylenediamine, and DNA binding studies, 10th Iranian Congress of Biochemistry & 3rd International Congress of Biochemistry and Molecular Biology, Tehran, Iran, November 16-19, 2009, Journal of Iranian Chemical Society, 6(Supple.)

44. J. Ezzati Nazhad Dolatabadi Soheila Kashanian, DNA binding study of 2-tert-butylhydroquinone and butylated hydroxyanisole using Circular Dichroism spectroscopy, ibid.

45. S. Kashanian, F. Abasi Tarighat, Bioconjugation of bovin seum albumin (BSA) to fluorescent isothiocyanate (FITC) and it’s binding studies by optical spectroscopy,ibid. p. S182

46. J. Ezzati Nazhad Dolatabadi, S. Kashanian, Investigation of DNA interaction with butylated hydroxyanisole using fluorimetery, ibid.

47. J. Ezzati Nazhad Dolatabadi, S. Kashanian, DNA binding study of 2-tert- butylhydroquinone using viscosimetery, ibid.

48. S. Kashanian, F. Abasi tarighat, R. Rafipour, Biomimetic Synthesis of Cobalt Nanoparticles using Apoferritin and its application in Electrochemical Reaction to detect Glucose in serum,14th European Congress on Biotechnology, Barcelona, Spain, September 13-16, 2009. Published in New Biotechnology, Volume 25, Supplement, Page S376,

49. S. Kashanian, J. Ezzati Nazhad Dolatabadi, Thermodynamic Studies of DNA Intercalative Food Additives, ibid, Page S365.

50. N. Shahabadi, S. Kashanian, F. Darabi, DNA interaction studies of a salen-type Schiff base ligand (N,N?-bis{5-[(triphenylphosphonium)-methyl]salicylidine}-o-phenylenediamine using circular dichroism and fluorescence techniques, ibid, Pages S35-S36.

51. S. Kashanian, Rafipour , F. Abasi Tarighat, Fabrication of cobalt nanoparticles in the cage-shaped protein, apoferritin, 10th Iranian Congress of Biochemistry & 3rd International Congress of Biochemistry and Molecular Biology, 16-19 November 2009, Tehran, Iran, Journal of Iranian Chemical Society, 6(Suppl.), p. S15

52. R. Rafipour, S. Kashanian, F. Abasi Tarighat, Synthesis of cobalt nanopaticles using apoferritin and Electrochemical studies on ferritin immobilized onto a self-assembled monolayer-modifed gold electrode, International Congress on Nanoscience and Nanotechnology, 9-11 November, 2010, Shiraz Iran.

53. F. Abasi Tarighat, S. Kashanian, R. Rafipour, Fabrication of CoO(OH) nanoparticles in the cavity of apoferritin and its application to design a biosensor based on direct electron transfer in Ferritin-NPs, International Congress on Nanoscience and Nanotechnology, 9-11 November, 2010, Shiraz Iran.

54. S. Kashanian, F. Jafary, Immobilization of bovine lactoperoxidase onto polyaniline polymer, 3rd Euchem. Congress, Germany, Nurnberg, Aug. 29- Sept. 2, 2010.

55. S. Kashanian, F. Jafary, Activity Assay of Immobilized lactoperoxidase onto polyaniline polymer, ibid.

56. M.M. Khodaei, S. Kashanian, H. Roshanfekr, DNA Cleavage Activity of Cu (II) Complexes, ibid.

57. M.M. Khodaei, S. Kashanian, H. Roshanfekr, DNA binding studies of Chloridazon using circular dichroism spectroscopy, ibid.

58. S. Kashanian, M.M. Khodaei, P. Pakravan, Interaction of isatin with DNA using spectrophotometric and circular dichroism Techniques, ibid.

59. M.B. Gholivand, S. Kashanian, H. Peyman, DNA-binding study of anthraquinone derivatives, ibid.

60. S. Kashanian, M. M. Khodaei, H. Roshanfekr, Study of ligand shape effect on DNA conformational change induced by Cu complexes, 4th International Conference on Experiments/Process/System Modeling/Simulation/ Optimization, 4th IC-EpsMsO, Athens, Greece, 6-9 July, 2011.

61. F. Kheirdoosh, J. E. Dolatabadi, S. Kashanian, Thermodynamic studies of DNA intercalative food additives, ibid

62. S. Kashanian, S. Heidary Zeidali, Circular dichroism (CD) and viscometric studies on tartrazine bound to calf thymus DNA, 12th Iranian Congress of Biochemistry & 4th International Congress of Biochemistry and Molecular Biology, Mashhad, Iran, Clinical Biochemistry, Volume 44, Issue 13, Supplement, 6-9 Sept. 2011, Page S233.

63. P. Pakravan, S. Kashanian, M.M. Khodaei, H. Adibi, In vitro study of DNA interaction with isatin-3-isonicotinylhydrazone using absorption, circular dichroism and viscosity studies, ibid, Page S173.

64. F. Jafary, S. Kashanian, Thermal stability studies of immobilized lactoperoxidase using polyaniline polymer, ibid, Page S240.

65. F. Jafary, S. Kashanian, F. Jafary, The stability studies of immobilized lactoperoxidase using polyaniline polymer against organic solvent, ibid, Page S240.

66. F. Jafary, S. Kashanian, F. Jafary, Immobilization of bovine lactoperoxidase onto polyaniline polymer: The effect of immobilization on the enzyme stability, ibid, Page S21.

67. S. Kashanian, Effects of tartrazine colorant on DNA structure, ibid, Page S232.

68. S. Kashanian, S. Heidary Zeidali, DNA binding studies of tartrazine food additive, ibid, Page S232.

69. S. Kashanian, S. Heidary Zeidali,Thermodynamic study on the binding of tartrazine food additive to calf thymus DNA, ibid, Page S233.

70. Z. Shariati, S. Kashanian, S. Askari, A. Tahmasian Ghobadi, S. Jvanmardi, Cytotoxicity Effect of ETU (a Pesticide Metabolite) on AGS Cell Line, The 17th National & 5th International Iranian Biology Conference, 5-7 Sept. 2012, Access number: IBC17thp4257T002-5.

71. Z. Shariati, S. Kashanian, S. Jvanmardi, Fluorometric Study of Fluoxetine-DNA Interaction, ibid, Access number: BC17thP6960T002-2.

72. Z. Shariati, S. Kashanian, S. Jvanmardi, Thermodynamic Interaction between Fluoxetine Antidepressant and DNA, ibid, Access number: IBC17thP6903T002-2.

73. S. Kashanian, S. Askari, DNA Binding Studies of Clodinafop- Propargyl, ibid, Access number: IBC17thP6344T002-2.

74. E. Rostami, S. Kashanian, The effect of ultrasound wave on Diagnosis and Treatment Patients Hypothyroidism, 1th Iranian Conference Application of nanotechnology in Diagnostic illness, June 2013, Abstract number 51.

75. E. Rostami, S. Kashanian, The effect of polyethylene glycol-coated chitosan nanoparticles on levothyroxine release, 16thIranian Chemistry Congress, September 2013, Abstract number P2180T7.

76. E. Rostami, S. Kashanian, M. Askari, The effect of ultrasound wave on levothyroxine release from chitosan nanoparticles, 4th International Conference on Ultrafine Grained and Nano-Structured Materials 05-06 November 2013, P2198


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